Academic Staffs

and anti-viral compounds searching

1. Suttiarporn P, Chumpolsri W, Wongpornchai S, Luangkamin S, Teepsawang S, LeardkamolkarnV. 2015.  Structures of Phytosterols and Triterpenoids with Potential Anti-Cancer Activity in Bran of Black Non-Glutinous Rice. Nutrients 7, 1672-1687; doi:10.3390/nu7031672

2. Bennukul K, Numkliang S, Leardkamolkarn V. 2014. Melatonin attenuates cisplatin induced hepatoma (HepG2) cell death via regulation of mTOR and ERCC-1 gene expression. World J Hepatol 6(4):230-242
3. Prangthip P, Surasiang  R,  Charoensiri  R,  Leardkamolkarn V, Komindr S,  Yamborisut U, Vanavichit A,  Kongkachuichai R. 2013.  Amelioration of hyperglycemia, hyperlipidemia, oxidative stress and inflammation in steptozotocin-induced diabetic rats fed a high fat diet by riceberry supplement. J Functional Food 5:195-203 (Impact factor 2.446) (Q1 Food Science & Technology)
4. Posuwan J,  Prangthip P, Leardkamolkarn V, Yamborisut U,  Surasiang R, Charoensiri R, Kongkachuichai R. 2013. Long-term supplementation of high pigmented rice bran oil (Oryza sativa L.) on amelioration of oxidative stress and histological changes in streptozotocin-induced diabetic rats fed a high fat diet; Riceberry bran oil.  Food Chem;138(1):501-508 (Impact factor  3.655) (Q1 Food Science & Technology)
5. Leardkamolkarn V, Sirigulpanit W, Chotiwan N,  Kumkate S, Huang  CY. 2012. Development of Dengue type-2 virus replicons expressing GFP reporter gene in study of viral RNA replication. Virus Res. 163(2):552-62 (Impact Factor 2.941)
6. Leardkamolkarn V, Sirigulpanit W. 2012. Establishment of a Stable Cell Line Co-expressing Dengue Virus-2 and Green Fluorescent Protein for Screening of Antiviral-compounds.  J Biomol Screen. 17(3):283-92 (Impact Factor 2.5)
7. Leardkamolkarn V, Sirigulpanit W, Purimsuk C, Kumkate S, Himakoun L, Sripanidkulchai BO. 2012. Inhibitory actions of Houttuynia cordata aqueous extract on dengue virus and dengue-infected cells. J. Food Biochem. 36(1):86-92 (Impact Factor  0.779)
8. Himakoun L, Tuchinda P, Puchadapirom P, Tammasakchai R, Leardkamolkarn V.  2011. Evaluation of genotoxic and anti-mutagenic propertiesof Cleistanthin A and Cleistanthoside A tetraacetate.Asian Pacific Journal of Cancer Prevention.12 :3271-3275 (Impact Factor 1.108)
9. Leardkamolkarn V, Thongthep W, Suttiarpornn W, Kongkachuicha R, Wongpornchai S, Wanavijitr A.  2011. Chemopreventive properties of the bran extracted from a newly-developed Thai rice; the Riceberry.Food Chemistry125:978-985 (Impact Factor 3. 458)
10. Leardkamolkarn V, Sirigulpanit W, Kinney RM. 2010. Characterization of recombinant dengue-2 virus derived from a single nucleotide substitution in the 5' non coding region.  Journal of Biomedicine and Biotechnology Volume 2010, Article ID 934694, 8 pages (Online) doi:10.1155/2010/934694 (Impact Factor 2.563)
11. Leardkamolkarn V, Tiamyuyen S, and Sripanidkulchai B.  2009. Pharmacological activity of Kaempferia parviflora extracts against human bile duct cancer cell lines. Asian Pacific Journal of Cancer Prevention; 10 (4):695-698(Impact Factor 1.108)
12. Kumkate S,  Onmek N,  Boonburapong B,  Singhakaew S, Leardkamolkarn V.  2009.  Estrogen-related fecundity reduction of lymnaea ollula following fasciola gigantica infection.  Journal of Parasitology 95(6):1391-1396). (Impact Factor 1.165)
13. Sirigulpanit W, Kinney RM, Leardkamolkarn, V.  2007. Substitution or deletion mutations between nucleotides 55-69 in the 5’ noncoding region of dengue type 2 virus produce variable effects on virus viability. Journal of General Virology. 88:1748-1752  (Impact Factor 3.110)
14. Borrirukwanit B, Lafleur MA, Mercuri FA, Blick T, Price JT, Fridman R, Pereira JJ, Leardkamonkarn V, Thompson EW. 2007.  The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by αVβ3 integrin in human breast cancer cells.   Matrix Biology 26:291-05  
    (Impact Factor 3.674)
15. Luplertlop N,  Misse D,  Bray D,  Deleuze V, Gonzalez J-P,  Leardkamolkarn V,  Yssel H, Veas F. 2006.  Dengue-virus-infected dendritic cells trigger vascular leakage through metalloproteinase over production.  European Molecular Biology Organization (EMBO reports), Nov. 7 (11);1176-1181 (Impact Factor 10.086)
16. Pongchai-rerk U, Guan JL, Leardkamolkarn V. 2005.   Focal adhesion kinase and Src phosphorylations in HGF-induced proliferation and invasion of human cholangiocarcinoma cell line, HuCCA-1. World J Gastroenterology, 11(37): 5845-5852  (Impact Factor 2010: 2.092)
17. Leelawat K, Engprasert S, Tujinda S, Suthipintawong C, Enjoji M, Nakashima, M, Watanabe T, Leardkamolkarn V. 2005.   Receptor-binding cancer antigen expressed on SiSo cells can be detected in metastatic lymph nodes from gastrointestinal cancers. World J Gastroenterology, 11(38): 6014-6017 (Impact Factor 2010: 2.092)
18. Leelawat K, Engprasert S, Pongchai-rerk U, Tujinda S, Suthipintawong C, Leardkamolkarn V. 2004.   No expression of Human Leukocyte Antigen G (HLA-G) in colorectal cancer cells. J Med Assoc Thai 87(7):816-818 (Impact Factor 0.075)
19. Leelawat K, Watanabe T, Enjoji M, Nakajima M, Tujinda S, Suthipintawong C, Leardkamolkarn, V.  2003.  Increase serum level of RCAS1 antigen in cholangiocarcinoma patients correlates with tissue level of RCAS1 mRNA and protein expression. J Hepatol, 38:101-101
    (Impact Factor 5.283)
20. Leelawat, K., Watanabe, T., Nakajima, M., Tujinda, S., Suthipintawong, C., and Leardkamolkarn, V.  2003.  Up regulation of tumor-associated antigen RCAS1 is implicated in high stages of colorectal cancer. J Clin Pathol  56(10):764-768 (Impact Factor 2.966)
21. Leardkamolkarn V, and Matsuo S. 2002. The glomerular reconstruction in acute mesangial glomerulonephritis is induced by specific Thy-1 epitopes on the mesangial cell surface. J.E.M. Soc. Thailand 16 (1): 91
22. Nuntakarn, L., Meevatee, U., Witayachumnarnkul, B., Leardkamolkarn, V., and Fuchareon, S. 2002.  Application of micro-FISH for characterization of structural human chromosome abnormalities.  Science Asia 28:1-9 (Impact Factor 0.176)
23. Leardkamolkarn, V. 1998. Review Article: Basement Membrane : Ultrastructure, Components and Immunolocalization. J.E.M. Soc. Thailand  12(1) : 37-49
24. Leardkamolkarn, V., N. Kurucharoen, and B. Withyachumnarnkul. 1997. Fine structure, development, and basement membrane components of coelomic sac of giant freshwater prawn, Macrobrachium rosenbergii de Man. J.E.M. Soc. Thailand 11(2) : 59-70
25. Pinson, H. D., Tucker D.C., St. John P., Leardkamolkarn V, Accavitti M.A,. Abrass C.K, and Abrahamson D.R.. 1996. Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic kidneys. Amer J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F886-F899 (Impact Factor 4.263)
26. Van den Heuvel, G.B., Leardkamolkarn V., St.John P., and Abrahamson D.R. 1996.  Carboxy terminal sequence and synthesis of rat kidney laminin gamma-1 chain.  Kidney Int. 49:752-760 (Impact Factor 4.927)
27. Leardkamolkarn, V.  1996.  Excessive production of extracellular matrix limited the formation of vesicles in polycystic ovarian (PCO) disease.  J.E.M. Soc. Thailand 11(1)  
28. Van den Henval, G.B., St. John P., Leardkamolkarn V., and Abrahamson D.R. 1994.  Temporally and spatially regulated expression of rat kidney laminin B2. J. Amer. Nephrol.  p.821
    (Impact Factor 7.505) 
29. Toskulkao, C., Deechakawan W., Leardkamolkarn V., and Glinsukon T. 1994.  The low calorie natural sweetener sterioside: Nephrotoxicity and its relationship to urinary enzyme excretion in the rat. Phytotherapy Res. 8:281-286 (Impact Factor 1.192)
30. Leardkamolkarn, V., and D.R. Abrahamson. 1992.  Immunoelectron microscopic-localization of laminin in rat ovarian follicles.  Anat. Rec. 233:41-52 (a photograph in this article was selected to be printed on the Journal’s cover) (Impact Factor 1.444) 
31. Fogel, M.A., Boyd, C.D., Leardkamolkarn V., Abrahamson D. R., Minto A W.M., and. Salant D.J.  1991. Glomerular basement membrane expansion in passive Heymann Nephritis.  Absence of increased synthesis of type IV collagen, laminin, or fibronectin.  Am. J. Pathol. 138:465-475 (Impact Factor 5.796)
32. Abrahamson, D.R., and Leardkamolkarn V. 1991. Development of kidney tubular basement membranes.  Kidney Int. 39:382-391 (Impact Factor 4.927)
33. Chinsethagij, K., Withyachumnarnkul B., Poolsanguan B., Leardkamolkarn V., and.Somana R.  1991.  Major cell types in the optic lobe of the giant freshwater prawn, Macrobrachium rosenbergii de man.  J.E.M. Soc. Thailand 5:9-23
34. Leardkamolkarn, V., Salant D.J., and Abrahamson D.R. 1990. Loss and rearrangement of glomerular basement membrane laminin during acute nephrotoxic nephritis in the rat.  Am. J. Pathol.
    137:187-198 (Impact Factor  5.796)
35. Chinsethagij,K., Withyachumnarnkul B., Leardkamolkarn V., Trakulrungsi W., Sobhon P., and Poolsanguan B..  1990.  The sinus gland of the giant freshwater prawn, Macrobrachium rosenbergii de man, as revealed by scanning electron microscopy. J.E.M. Soc. Thailand 4:43-50
36. Leardkamolkarn, V., Heck L.W., and Abrahamson D.R. 1989. Gonadectomy induces laminin biosynthesis and basement membrane assembly in anterior pituitary glands of adult rat.  Cell Tissue Res. 257:587-596 (Impact Factor 2.383)
37. Leardkamolkarn, V., and Abrahamson D.R. 1988. Binding of intravenously injected antibodies against laminin to developing and mature endocrine glands. Cell Tissue Res. 251:171-181 (Impact Factor 2.383)
38. Leardkamolkarn, V., Somana R., Rojananuengni S., and Tosukhowong P. 1986.  Failure of inducing spermatogenesis with FSH, LH and testosterone in vitamin A deficient rat. 
    J.E.M. Soc. Thailand 4:43-50
39. Leardkamolkarn, V., Somana R., Rojananuengnit S., and Tosukhowong P. 1986.  Failure of inducing spermatogenesis with FSH, LH and testosterone in vitamin A deficient rat.  Thai J. Pharmacol. 8:153-160
40. Sasaluxananon, S. Somana R., Leardkamolkarn, V., and Sripairojthikoon W. 1983. Decrease in pituitary growth hormone level in rat after prolong administrations of bovine thyrotropin. Thai J. Pharmacol. 5:71-76
41. Visessuwan, S., Sriaroon U., Leardkamolkarn, V., and Supaluxanagorn M. 1983. Roles of L-monosodium glutamate in sterility. Science (Thailand) 37:699-700.
42. Sripairojthikoon W, and Leardkamolkarn, V 1982.  Anatomical observation on the mylohyoid bridge: An anomalous derivative of Meckel’s cartilage, in the Thai. M. Dent. J. 3:76-85
43. Leardkamolkarn, V., and Sripairojthikoon W.  1981.  Anomalies of the mylohyoid groove of the mandible. M. Dent. J. 2:85-90 

Patenting

1. “Genetic engineering of dengue virus type-2 mutants containing specific 5’NCR nucleotides substitution and their derived viruses”  by Vijittra  Leardkamolkarn (PI) 
   Patent filed: by NSTDA & Mahidol University (Patent # 0701002089, dated April 27, 2007)
2. “Construction of mammalian cell-based model co-expressing subgenomic dengue virus genome and green fluorescent protein for effective anti-viral drug screening” by Vijittra  Leardkamolkarn (PI)  Patent filed: by Mahidol University & CHE (Patent # 1001000830, dated June 4, 2010)